The 8-in-1 BioSerum is Defenage's iconic bestseller. The remarkably smart formula seems to understand your skin’s needs better than your own DNA. Designed to activate, orchestrate and energize, this biologically-advanced anti aging cream-like serum concentrate provides an unprecedented concentration of defensin molecules contained in theAge-Repair Defensin®Complex. Dermatologists and aesthetic professionals name defensins as a perfect retinol alternative and the 8-in-1 BioSerum as a retinol serum replacement. The best part? Results are equal to 8 separate serums.